BRD 8430 ( BRD8430 )

产品货号. M12045 CAS No. 1482499-16-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

BRD 8430
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively.
产品描述

BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively; shows no activity against other HDACs; decreases viability and induces differentiation of neuroblastoma cell lines.
同义词

BRD8430
通路

Cell Cycle/DNA Damage
靶点

HDAC
受体

HDAC
研究领域

——
适应症

——

CAS Number

1482499-16-0
分子量

573.74
分子式

C33H43N5O4
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

N-(2-aminophenyl)-4-[[[(2R,3S)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl-methylamino]methyl]benzamide

1. Frumm SM, et al. Chem Biol. 2013 May 23;20(5):713-25.

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产品手册

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